The basic specifications of Size 4 gelatin capsules are as follows:
Volume capacity: approximately 0.13 ml (130 mg) to 0.20 ml (200 mg)
External diameter: approximately 6.50 mm
Length: approximately 14.3 mm
Actual fill weight may vary depending on the density and other physical properties of the material being filled.
Like other gelatin capsules, Size 4 capsules
are typically made from two cylindrical sections that fit together to form a capsule shell. The shell is usually made from a combination of gelatin and water, which gives it a soft, flexible texture that can be easily swallowed. The capsule shell is also designed to dissolve quickly in the digestive tract, allowing the contents of the capsule to be released and absorbed by the body.
Size 4 gelatin capsules are smaller than the larger sizes (such as Size 0 or Size 00) and are typically used for products that require a lower dose or for patients who have difficulty swallowing larger capsules or tablets. They are commonly used for a variety of products, including dietary supplements, herbal remedies, and over-the-counter medications.
Why Size 4 Gelatin Capsule Was Born
Size 4 gelatin capsules were developed as an even smaller alternative to the existing gelatin capsule sizes. The smaller size was designed to offer even greater flexibility in dosing and to make it easier for patients to swallow.
While Size 3 capsules are smaller than the larger sizes, some individuals may still find them difficult to swallow. Size 4 capsules are even smaller in diameter, making them easier to swallow for some individuals, especially pediatric or geriatric patients, or those who have difficulty swallowing larger dosage forms.
The smaller size of the capsule also allows for greater flexibility in dosing, as it can be filled with a smaller amount of material than a Size 3 capsule, allowing for more precise dosing. This can be especially important for products that require very low doses or need to be titrated up or down based on individual patient needs.
In addition, some manufacturers prefer to use Size 4 capsules for certain products, as the smaller size can make the final product more compact and easier to package and transport. This can be especially important for products that are sold in large quantities or require a lot of storage space.
The development of Size 4 gelatin capsules was driven by the desire to provide an even smaller, more convenient dosage form that could meet the needs of a wider range of patients and product applications.